Amantadine is a drug used as an antiviral and an anti-Parkinson’s disease treatment.
How it works
Amantadine is known as a dopamine promoter. It can prompt the body to release more dopamine by blocking dopamine reuptake by the neurons in the brain. These properties of Amantadine were long considered to be effective in treating Parkinson’s disease, a neurological condition connected to dopamine levels in the body. It also used to be prescribed as an antiviral drug to prevent influenza type A, better known as the common cold.
Amantadine is approved by the FDA to treat Parkinson’s and as an antiviral agent. However, the Centers for Disease Control no longer recommend Amantadine for treatment as an antiviral against influenza in the United States. Other research has also suggests that effectiveness of Amantadine against Parkinson’s is undetermined and lacks substantive evidence.
Amantadine may be prescribed for treating and preventing types of fly virus. It may also be recommended to treat uncontrolled muscle movements caused by Parkinson’s disease and certain types of medications. Physicians may prescribe the drug for other conditions as well.
Dosage will be determined by the type of the condition being treated, physician recommendation among other concerns.
The normal recommended dose of Amantadine 100mg per day. The tablets should be taken orally in a single dose or two divided doses. The twice daily dose is recommended if the drug causes side effects affecting the central nervous system.
For Parkinson’s disease, the recommended dose is 100mg oral tablets taken twice a day.
Follow the dosage instructions exactly as prescribed by your doctor for the treatment to be effective. Stick to a dosage schedule to avoid missing doses.
Swallow tablets whole without breaking or crushing. You can take Amantadine with or without food.
Try not to take double doses to make up for a missed dose. If you do miss a dose, take it soon as possible only if the next dose is not due soon.
When taking Amantadine for influenza, it’s very important to follow the complete dosage schedule, even if you feel better. Stopping treatment prematurely may cause the viral infection to return.
Amantadine may cause the following side effects:
Seeing, hearing or feeling things that are not there
Swelling of the hands, feet or lower legs
The above symptoms are not common. However, if they do occur and persists or gets worse over time, immediately seek medical attention.
Do not take Amantadine if you are allergic to any of the ingredients in the medicine.
Amantadine may not be safe to use for patients with uncontrolled narrow-angle glaucoma, history of heart disease, seizures, mood problems, or hypotension.
Pregnant women, nursing mothers or women who plan on becoming pregnant soon must consult with a doctor before taking Amantadine for influenza.
Do not operate heavy machinery or engage in activities like driving that requires staying alert if Amantadine causes dizziness or lightheadedness.