Kytril is a medication that can prevent nausea or vomiting after surgery or cancer treatments.
How it works
Kytril, also known as Granisetron, belongs to a group of drugs known as 5-HT3 receptor antagonists. Kytril can block serotonin, a neurotransmitter in the brain, that causes vomiting and nausea.
Kytril is used to prevent nausea and vomiting caused after chemotherapy, radiation therapy or certain surgeries. This medication may be prescribed for conditions other than the ones mentioned here.
Your doctor will prescribe the correct amount of Kytril to take to control your condition.
Kytril tablets should be taken by the mouth. You should take each tablet about an hour before the cancer treatment begins. The follow-up second dose should be taken 12 hours after the first unless your doctor instructs otherwise.
You should take Kytril exactly as your doctor tells you to take it. Do not take this medication in doses more or less than prescribed. Doing so may worsen your condition and hinder treatment.
You may be at risk of an overdose if you take more than the amount prescribed. Overdose symptoms of Kytril include headaches.
Read the directions on the medicine package before taking the drug. Follow the instructions carefully. If you don’t understand the instructions, ask your doctor or a nurse.
Kytril may cause one or more of the following side effects:
Difficulty falling asleep or staying asleep
Tell your doctor right away if any of the above side effects do not disappear or becomes unbearably severe.
Side effects other than the ones listed above could occur. If one does occur, immediately inform your doctor.
Some side effects may be severe than others. Inform your doctor immediately if you experience any of these rare but severe side effects: nausea, vomiting, agitation, hallucinations, fever, flushing, excessive sweating, confusion, diarrhea, loss of coordination, stiff or twitching muscles, seizures, coma or loss of consciousness.
Do not take Kytril if you are allergic to this medication. If you are allergic to the following medications, you may be allergic to Kytril as well: ondansetron (Zofran, Zuplenz), alosetron (Lotronex), palonosetron (Aloxi, in Akynzeo) and dolasetron (Anzemet). Make sure you are not allergic to any of the inactive ingredients in the drug either.
Disclose any other prescription medication, over-the-counter drugs, nutritional supplements, vitamins or herbal remedies you may be taking to your doctor before starting Kytril treatment.
Kytril may interact negatively with certain medications, including lithium, migraine drugs like almotriptan, fentanyl, monoamine oxidase (MAO) inhibitors, fluoxetine and paroxetine. Ask your doctor if Kytril is safe to take with any other drugs you are taking at the same time.
Kytril may not be safe to take if you are pregnant, breastfeeding or are planning to become pregnant.
It is not necessary to change your diet when taking Kytril unless your doctor instructs you to.
Do not take Kytril on a regular scheduled basis. It should only be taken before and after surgery or cancer treatments.